Radiation Oncology/Toxicity/Small bowel

Small Bowel

Acute GI toxicity


Roeske JC, Mundt AJ et al. Radiother Oncol (2003)

  • Keep V45 <= 250 cc

  • North Central Cancer Treatment Group, 2007 PMID 17401014 -- "Patient assessment of bowel function during and after pelvic radiotherapy: results of a prospective phase III North Central Cancer Treatment Group clinical trial." (Haddock MG, J Clin Oncol. 2007 Apr 1;25(10):1255-9.)
    • Prospective. Data gathered as part of randomized trial evaluating sucralfate.
    • Bowel movements: increased up to week 4, then slowly decreased. At baseline: median 1 BM. At 1 year: median 2 BMs
    • Normalized symptoms: at 1 year: frequency, nocturnal BM, cramping, bleeding
    • Persistent symptoms at 1 year: urgency, clustering, incontinence