Radiation Oncology/RTOG Trials/0319

RTOG 0319 (Breast)
 Title: A Phase I/II Trial to Evaluate 3DCRT Confined to the Region of the Lumpectomy Cavity for Stage I and II Breast Carcinoma
 Objective:
 Protocol:
 38.5 Gy Total/10 fractions (3.85 Gy per fraction), 2 fractions/day (separated by 6 hours), Given in 5 consecutive working days
 Radiotherapy should begin within eight weeks of surgery (If chemotherapy is given first, RT begins 2 weeks after the last cycle of chemotherapy)
 Eligibility:
 Invasive pathology; AJCC Stage III; single focus
 Negative surgical margin; up to 3 LN+
 Enrollment Target: 46 patients
 Activation: August 15, 2003
 Closed: April 30, 2004