Radiation Oncology/Online tools

Online Tools

Radiobiology

Linear Quadratic / BED / EQD Calculators:

2 Gray Equivalent Calculator (Kathmandu, Nepal)
- Gives 2 Gy equivalent dose at different α/β.
Site down: ~~http://www.radiotherapy.com/calculate Radiotherapy Dose Calculator (radiotherapy.com)~~ - BED, alpha-beta calculator (Java applet)
RBApp - BED, EQD2, alpha-beta calculator (Web App, Android, BlackBerry)
eLQ - linear quadratic calculator

Brachytherapy:

See "calculation tools" at: Radiation_Oncology/Cervix/Brachytherapy#Equivalent_doses
- e.g. HDR vs LDR BED calculations

Bladder Cancer

Breast Cancer

Ipsilateral Breast Tumor Recurrence
- Invasive Disease
  - IBTR!- https://www.tuftsmedicalcenter.org/ibtr/
    - 10-year prediction of ipsilateral breast cancer recurrence after BCS and axilla evaluation, with and without RT
    - 2010: PMID 20048188 -- "Validation of a Web-Based Predictive Nomogram for Ipsilateral Breast Tumor Recurrence After Breast Conserving Therapy." (Sanghani M, JCO)
  - IBR - http://research.nki.nl/ibr/ibr/index.html
    - 10-yr prediction of ipsilateral breast recurrence free probability for RT w/ or w/o boost.
    - 2011: PMID 21821304 -- "Nomogram to predict ipsilateral breast relapse based on pathology review from the EORTC 22881-10882 boost versus no boost trial." (van Werkhoven, RO)
- DCIS
  - MSKCC DCIS Recurrence Calculator - http://nomograms.mskcc.org/Breast/DuctalCarcinomaInSituRecurrencePage.aspx
    - Estimates 5 and 10 yr risks of ipsilateral recurrence after lumpectomy and different adjuvant therapy choices (eg RT, endocrine therapy)
    - 2010: PMID 20625132 -- "Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ." (Rudloff, JCO)

Risk of Positive Nodes
- Probability of Finding Additional Positive Nodes AFTER Sentinel Lymph Node Biopsy (SLNBx):
  - MSKCC Additional Node Nomogram - http://nomograms.mskcc.org/Breast/BreastAdditionalNonSLNMetastasesPage.aspx
    - Predicts probability of finding more positive nodes on completion axillary dissection after positive SLNBx.
    - 2003: PMID14654469 -- A nomogram for predicting the likelihood of additional nodal metastases in breast cancer patients with a positive sentinel node biopsy." (Van Zee, ASO)
  - MDACC Additional Nodes WITHOUT Neoadjuvant Chemotherapy - http://www3.mdanderson.org/app/medcalc/bc_nomogram2/index.cfm?pagename=nsln
    - Predicts probability of finding more nodes on completion axillary dissection after positive SLNBx in patients who have NOT received neoadjuvant chemotherapy.
    - 2010: (Mittendorf, SABC)
  - MDACC Additional Nodes AFTER Neoadjuvant Chemotherapy - http://www3.mdanderson.org/app/medcalc/bc_nomogram/index.cfm?pagename=nsln
    - Predicts probability of finding more nodes on completion axillary dissection after positive SLNBx in patients who have received neoadjuvant chemotherapy.
    - 2008: PMID 18442039 -- "Factors Predicting Additional Disease in the Axilla in Patients with Positive Sentinel Nodes after Neoadjuvant Chemotherapy." (Jeruss, Cancer)
Breast Cancer Risk Assessment Tool (NCI) - risk of developing breast cancer
- link

Cholangiocarcinoma

Colon Cancer

Glioblastoma

Gallbladder

Lung Cancer

Oral Cavity Cancer

Pancreas

Renal Cell

Prostate

MSKCC Prostate Cancer Nomograms - multiple outcomes
PSA doubling time calculator:
- RTOG - opens Excel spreadsheet
- Bellera (PDF) - graph paper method
University of Michigan PSACalc - see PMID 19014779 "Determinants of Change in Prostate-Specific Antigen Over Time and Its Association With Recurrence After External Beam Radiation Therapy for Prostate Cancer in Five Large Cohorts." (Proust-Lima C, Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):782-91)
The Palpable Prostate blog - PSA Doubling Time. Provides a number of links to doubling time calculators
Doubling Time - by Roth V. - Graphs (linear) and computes doubling time
prostatecancerwatchfulwaiting.co.za - Excel spreadsheet. PSA Calculator. Graphs semi-log but only graphs PSA values > 1.0.

Sarcoma

Cancer Survivorship

OncoLife - University of Pennsylvania
- Create individualized survivorship plans of care based on the Institute of Medicine recommendations for cancer survivors.

About Radiation Oncology

RT Answers - American Society for Radiation Oncology (ASTRO)
- Information on radiation therapy written for patients by physicians and other members of the radiation oncology treatment team.