Radiation Oncology/Mortality

Radiation Mortality

• Royal Sussex County Hospital, UK; 2013 PMID 23727432 -- "A national standard for early mortality after external beam radiotherapy?" (Osborne GE, Clin Oncol (R Coll Radiol). 2013 Sep;25(9):565. doi: 10.1016/j.clon.2013.04.011. Epub 2013 May 31.)
  • Retrospective. 2 month period. Curative intent 57% versus palliative intent 43%
  • Outcome: 30-day mortality palliative cases 12.9%. Fractionation in patients who died <30 days: single 57%, 2-5 fractions 38%, 6-10 fractions 5%, none >10 fractions. 90-day mortality curative cases 2.3%

• Addenbrooke's Hospital, UK; 2012 -- "Mortality following palliative radiotherapy - are we overusing fractionated treatments?" (Treece SJ, Jephcott CR) Conference abstract
  • Retrospective. 124 patients completing palliative therapy in 01/2011.
  • Outcome: 30-day mortality 8.9%; 6-week mortality 19.3%

• St James Institute of Oncology, Leeds, UK; 2012 (2004-2010) -- "30 and 90 day mortality after 40,670 courses of external beam radiotherapy in unselected patients (Sebag-Montefiore D, et) Conference abstract
  • Retrospective. 7 years. Treatment intent radical 30%, adjuvant 29%, palliative 41%
  • Outcome: 30-day mortality radical 3.0%, adjuvant 0.8%, palliative 12%; 90-day mortality radical 4.8%, adjuvant 17%, not given for palliative