Radiation Oncology/Corporate/Protons

Proton Therapy

  • Please see the Protons page for links to clinical information


Existing Proton FacilitiesEdit

North America




Chronologic List Overview

Facility Country Start Particle Comments
Lawrence Berkeley Laboratory USA 1955 Proton, Heavy Ion
Svedberg Laboratory Sweden 1957 Proton New facility Uppsala, 1988
Harvard Cyclotron USA 1961 Proton New facility in 2001
JINR Russia 1964 Proton New facility 1989
ITEP Russia 1969 Proton
PNPI Russia 1975 Proton
Chiba Japan 1979 Proton
Tsukuba Japan 1983 Proton
PSI Switzerland 1984 Proton
JINR Russia 1989 Proton
Uppsala Sweden 1989 Proton
Clatterbridge UK 1989 Proton ocular only
Loma Linda USA 1990 Proton first hospital-based
Nice France 1991 Proton
Orsay France 1991 Proton
LOuvain Belgium 1991 Proton low energy only
iTHEMBA South Africa 1993 Proton
MPRI USA 1993 Proton
UCSF / UC Davis USA 1994 Proton ocular only
Chiba Japan 1994 Carbon first ion
TRIUMF Canada 1995 Proton ocular only
GSI Germany 1997 Carbon
HMI Germany 1998 Proton ocular only
NCC Japan 1998 Proton
Hyogo Japan 2001 Proton, Carbon
Harvard USA 2001 Proton
Catana Italy 2002 Proton ocular only
Shizuoka Japan 2002 Proton
Wakasa Japan 2002 Proton
Wanjie China 2004 Proton
MD Anderson USA 2006 Proton
University of Florida USA 2006 Proton
Southern Tohoku PTC Japan 2008 Proton
Rinecker PTC Germany 2009 Proton
Oklahoma ProCure USA 2009 Proton
Heidelberg HIT Germany 2009 Proton/Carbon
University of Pennsylvania USA 2010 Proton
Hampton University USA 2010 Proton
CDH ProCure Chicago USA 2010 Proton
CNAO Italy 2011 Proton/(Carbon)

Proposed Proton FacilitiesEdit

United States


Middle East



Treatment PlanningEdit

Patient PositioningEdit

  • Brindisi, Italy; 2010 PMID 20465816 -- "Patient positioning in the proton radiotherapy era." (Devicienti S, J Exp Clin Cancer Res. 2010 May 13;29(1):47. [Epub ahead of print])
    • Review of various robotic couch applications

Overview by InstitutionEdit

  • Heidelberg, Germany; 2010 PMID 20831505 -- "Heidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients." (Combs SE, Acta Oncol. 2010 Oct;49(7):1132-40.)
  • CNAO Italy; 2009 PMID 19579862 -- "The National Center for Oncological Hadron Therapy: status of the project and future clinical use of the facility." (Orecchia R, Tumori. 2009 Mar-Apr;95(2):169-76.)
    • Overview of plans for the facility
  • Hyogo Japan; 2009 PMID 19920379 -- "[Current status and future of particle radiotherapy at the Hyogo Ion Beam Medical Center]" [Article in Japanese] (Murakami M, Gan To Kagaku Ryoho. 2009 Nov;36(11):1791-4.)
    • Overview. 2,639 patients treated with prostate, H&N, liver, lung and sarcomas (total 87%). Proton beam 2,122 (80%), carbon ion 517 (20%)
  • European ENLIGHT network
    • 2008 PMID 18208851 -- "COST-ENLIGHT strategic workshop on hadron (particle) therapy, CERN, Geneva, 3-4 May 2007." (Taylor RE, Br J Radiol. 2008 Mar;81(963):169-71. Epub 2008 Jan 21.)
      • Overview of meeting to review current status of hadron therapy in Europe
    • 2007 PMID 17513898 -- "European developments in radiotherapy with beams of large radiobiological effectiveness." (Amaldi U, J Radiat Res (Tokyo). 2007;48 Suppl A:A27-41.)
      • Overview of European experience, including development of facilities in Heidelberg (HIT) and Pavia (CNAO). Also review of Marburg, Wiener Neustadt, Lyon and Uppsala and the development of ENLIGHT network
  • Paul Scherrer Institut; 2007 PMID 17878101 -- "[Proton beam therapy: clinical indications and summary of the Swiss experience] - [Article in French]" (Weber DC, Bull Cancer. 2007 Sep 1;94(9):807-15.)
  • Harvard
    • 2007 PMID 17668954 -- "Clinical proton radiation therapy research at the Francis H. Burr Proton Therapy Center." (DeLaney TF, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):61-6.)
      • Review of MGH current clinical research goals
    • 1980 PMID 6245096 -- "Clinical experience with proton beam radiation therapy." (Suit HD, J Can Assoc Radiol. 1980 Mar;31(1):35-9.)
      • Cannot yet assess efficacy, but results warrant further investigation
  • Loma Linda; 2007
    • 2007 PMID 17668955 -- "Development and operation of the Loma Linda University Medical Center proton facility." (Slater JD, Technol Cancer Res Treat. 2007 Aug;6(4 Suppl):67-72.)
      • Overview of a hospital-based center development
    • 2006 PMID 16551128 -- "Clinical applications of proton radiation treatment at Loma Linda University: review of a fifteen-year experience." (Slater JD, Technol Cancer Res Treat. 2006 Apr;5(2):81-9.)
      • Review of 15 year experience using protons

Other EntitiesEdit