The hitting in this game is rather simple. All you have to have is the right timing to get the bat on the ball. If it is timed right, you get a better hit. The player should usually hit the inside pitches to your batter sooner than the outside pitches. Also you want to remember to aim up for home runs and down for ground balls. And the harder you swing, the harder you hit the ball. Lastly always remember splitters in this game are 99 times out of 100 going to be balls. How can you tell if the pitch is going to be a splitter? When the pitcher releases the ball, the ball looks like the seams don't move very much. If they aren't moving, then lay off.
Pitching is the real key and hardest part of this game. You have 4 pitches to choose from. The fastball(hold nothing), the screwball(hold A button), the curveball(hold B button), and the splitter(hold both A and B buttons). Each ball has a unique purpose and each ball can be thrown fast or slow depending on how much whip action you put on the controller. The fastball has two purposes: it can be used to blow by the batter, usually about 93-94mph, or it can be used like a change-up when it is thrown softly. The screwball for a right handed pitcher moves inside to a right handed batter. The curveball for a right handed pitcher moves outside to a right handed batter. And lastly the splitter moves down to any batter. The best part about a splitter is it can almost never be hit in play for a hit, the worst part is it is almost never a strike, so people can lay off of it if they learn to read the seams of the ball. You can also move the pitch either up, down, left, or right by pressing the D-pad in that direction, it can be pressed 2 times in one direction furthering the position away from the center of the plate. Finally the 1 and 2 buttons on the Wii-mote change the pitch from being thrown over-hand (the 1 button) and side-arm (the 2 button). After you get past the initial trial of using the pitches and knowing what they do, now the strategy is just like any other pitcher's. Try to change speeds well, by using a fastball and then a slow curve. Change up speeds and when they least expect it, use a splitter to get the strike out. Also this comes from knowing your opponent. If they're a person who has only hits fastballs out of the park then throw him some change-ups (slow fastballs) or some splitters. It takes practice but it can become very easy to fool hitters.