User:Katsadler/sandbox

A brief overview of strokes edit

Strokes account for around 6% of all deaths in Australia[1] and cost the economy $5 billion every year.[2] Those who survive are often left with cognitive and/or physical disabilities,[3] so it is not surprising that two-thirds of the 420,000+ stroke survivors in Australia are dependent on another person for their daily needs.[2] With such significant health and economic impacts, a strong focus on preventing strokes is vital.

 
The most common type of stroke is an ischemic stroke, which is caused by atherosclerosis (a build up of plaque) in the arteries feeding the brain. Source: Blausen Medical Communications, Inc.

Mitigating the risk of stroke through exercise edit

Aerobic exercise, in which the heart rate and breathing rate are elevated, has long been linked to a decrease in the risk factors associated with cardiovascular disease (CVD), such as diabetes, hypertension (high blood pressure) and dyslipidemia (cholesterol problems), which in turn decreases the likelihood of having a stroke.[4] The Australian Health Department recommends a minimum 150-300 minutes of moderate intensity physical activity or 75-150 minutes of vigorous intensity physical activity per week to improve cardiovascular function.[5]

Background to this research edit

Stroke survivors face a high risk of recurrent stroke because the majority have CVD, thus exercise should be included in rehabilitation programs.[6] However, many survivors suffer from physical impairment and/or cognitive dysfunction which make it difficult for them to partake in moderate or vigorous intensity physical activity.[7] They may still be able to undertake non-aerobic exercise, that is lower-intensity physical activity such as resistance training or mobility exercises. A 2014 Canadian study aimed to compare the effects of aerobic and non-aerobic exercise on cardiovascular function in stroke survivors.[7]

Where is the research from? edit

The study was conducted in Vancouver, Canada by a group of reputable researchers who have published extensively on exercise and strokes in peer-reviewed journals. No conflicts of interest were declared and the study was approved by the University of British Columbia Clinical Research Ethics Board.[7]

What kind of research was this? edit

The research was based on a single-blinded randomised controlled trial.[7] Meaning participants were assigned randomly to groups and researchers who assessed the outcomes had no knowledge of what program participants were involved in, thus reducing bias.[8] Researchers also followed guidelines established by the widely-endorsed CONSORT Group.[9]

What did the research involve? edit

The trial involved 50 participants, all of whom had suffered a stroke over 1 year ago but were able to walk at least 5 metres independently. Participants were divided into two equal-sized groups:

  • Aerobic exercise program
    • Participants in this group undertook various modes of walking and cycling.
    • Exercise intensity increased from 40% to 70-80% over the course of the trial.
  • Balance and flexibility program
    • Participants in this group undertook stretching, balancing and weight-bearing movements.
    • Exercise was non-aerobic in nature, meaning the intensity was kept below 40%.[7]

Each group partook in 3x60-minute classes per week for 6 months and underwent a variety of laboratory tests at the beginning and end of the trial to determine changes in VO2peak (a measure of aerobic capacity), functional mobility, cardiac function as well as blood glucose and cholesterol levels.[7] Classes were supervised and intensity was monitored using heart rate devices, two measures which would have ensured greater accuracy.[10] However, the findings could have been strengthened by including a control group.[11]

What were the basic results? edit

Key findings are shown below:

  • Neither group demonstrated an increase in VO2peak.
  • Only the group which undertook aerobic exercise showed improved cardiac function.
  • Both groups showed improvements in blood glucose and cholesterol levels, and an increase in functional mobility.[7]

The first finding was surprising because undertaking an aerobic exercise program typically improves cardiorespiratory fitness which in turn is reflected in higher VO2peak values.[12] Researchers suggested performance in VO2peak tests in this study may have been affected by physical and/or cognitive disabilities suffered by stroke survivors.[7]

What conclusions can we take from this research? edit

All stroke survivors should be encouraged to partake in some sort of physical activity. Aerobic exercise, such as walking or cycling at a moderate intensity, provides the most wide-ranging benefits. Those who are unable to partake in high intensity activities can consider alternatives including mobility exercises and resistance training in order to reduce the risk of CVD.[7]

Practical advice edit

Physical activity can improve health and increase independence in stroke survivors, but the type and intensity of exercise must be appropriate for each individual's physical and mental condition, and is best assessed by a qualified health professional. The chart below provides a variety of aerobic and non-aerobic exercise options for stroke survivors.

Aerobic Non-Aerobic
Walking (on flat ground or uphill) Stretching (yoga, pilates, tai chi)
Cycling (outdoor or on a stationary bicycle) Weight-bearing exercises (circuit training, free weights or weight machines)
Step-based activities (up stairs or on a stepper machine) Coordination and balance activities (for example shifting weight between feet and hands)

Source: Loosely based on http://circ.ahajournals.org/content/109/16/2031#T1 XXXXXXXX

Further information/resources edit

Basic information on strokes and reducing the risks see Stroke Foundation and Better Health.
For reliable information on exercising post-stroke see American Heart Foundation.
Health professional treating stroke patients may consult Informme.

  1. Australian Institute of Health and Welfare. AIHW website [Internet]. Canberra: AIHW; 2012, [cited 2016 Sep 23]. Available from http://www.aihw.gov.au.
  2. a b Deloitte Access Economics. The Economic Impact of Stroke in Australia. Canberra, 2013.
  3. Womack, C J. Stroke. In Ehrman, Jonathon K; Gordan, Paul M.; Visich, Paul S.; and Keteyian, Steven J. (Eds), Clinical Exercise Physiology (pp 559-569). 2013. Champaign, IL. Human Kinetics.
  4. Myers, Jonathan. Exercise and Cardiovascular Health. Circulation. 2003;107:e2-e5.
  5. Department of Health. Health Website [Internet}. Canberra: Health; 2016 [cited 2016 Sep 24]. Available from: http://health.gov.au.
  6. Boysen G, Truelsen T. Prevention of recurrent stroke. Neurol Sci. 2000;21:67–72.
  7. a b c d e f g h i Tang, Ada; Eng, Janice J.; Krassioukov, Andrei V.; Madden, Kenneth M.; Mohammadi, Azam; Tsang, Michael Y. C.; Tsang, Teresa S. M. Exercise-induced changes in cardiovascular function after stroke: a randomized controlled trial. International Journal of Stroke. 2014; 7: 883-889.
  8. Moher, David; Hopewell, Sally; Schulz, Kenneth F; Montori, Victor; Gøtzsche, Peter C; Devereaux, PJ; Elbourne, Diana; Egger, Matthias; Altman, Douglas G. CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials. BMJ 2010;340:c869.
  9. Shamseer, Larissa; Hopewell, Sally; Altman, Douglas G., Moher, David Moher; Schulz, Kenneth F. Update on the endorsement of CONSORT by high impact factor journals: a survey of journal "Instructions to Authors" in 2014. Trials 2016; 17:301.
  10. Prince SA; Adamo KB; Hamel ME; et al. A comparison of direct versus self-report measures for assessing physical activity in adults: a systematic review. Int J Behav Nutr Phys Act 2008;5:56.
  11. Fos, Peter J. Epidemiology Foundations: The Science of Public Health. San Francisco (CA): Jossey-Bass; 2011.
  12. Powers, Scott K; Howley, Edward T. Exercise Physiology. Sydney: McGraw Hill; 2014.