Structural Biochemistry/Cholesterol 24-hydroxylase

Some interesting facts about Cholesterol 24-hydroxylase:

1. It converts cholesterol to 24S-hydroxycholesterol. It then diffuses out from the brain and is metabolized in the liver.

2. It is a P450 enzyme is located in the endoplasmic reticulum, an organelle in all eukaryotic cells. It is an enzyme that is expressed in some but not all neurons of the brain.