Obstetrics and Gynecology/Preterm Labour
Labour occurring between 20 and 37 weeks gestation.
30% idiopathic
30% related to pre-labour rupture of membranes
The rest related to a myriad of other factors
Not-recommended for women in pre-term labour with intact membranes
Corticosteroids (betamethasone) should be administered to promote fetal pulmonary development. However, multiple doses should be approached with caution.
Using atosiban, indomethacin, nifedipine
Contraindications to tocolysis include
Non-reassuring fetal status
Dilated cervix >4cm
Suspected intrauterine infection
Gestational age >34 weeks or <23 weeks
Intrauterine fetal death
Fetal anomaly incompatible with life
Maternal deterioration necessitating delivery
Pre-Labour Rupture of the Membranes
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Pre-labor rupture of the membranes (PROM) may occur at pre-term or term dates. PROM poses a significant risk for pre-term labour.
PROM occurs in less than 30% of pregnancies.
Antibiotics will prolong the latent phase of labour, prevent/treat ascending infection, and reduce the incidence of complications with prematurity.