ID Board Review/Antimicrobial Therapy/Antibacterials

Cell Wall and Envelope Inhibition

β-Lactams

• Carbapenems
• Cephalosporins
• Monobactams (i.e. Aztreonam)
• Penicillins

Polypeptides

• Glycopeptides
• Glycolipopeptides and Lipopeptides

Protein Synthesis Inhibition

30S Inhibitors

• Aminoglycosides
• Tetracyclines

50S Inhibitors

• Oxazolidinones
• Lincosamides
• Macrolides
• Streptogramins

Nucleic Acid Inhibition

Quinolones

• Fluoroquinolones

Anaerobic DNA Inhibition

• Nitroimidazoles

Bacterial Dependent RNA Synthesis Inhibition

• Rifamycins
• Lipiarmycins

Miscellaneous

• Non-sulfonamide (sulfa drug), Non-trimethoprim urinary tract agents
• Topical antibacterials
• Other routes of administration