A-level Chemistry/OCR (Salters)/Engineering Proteins

Engineering Proteins is the eighth unit in the Salters Advanced Chemistry course.

A ribbon diagram of the human insulin hexamer, showing two Zn²⁺ ions and the histidine residues that ligate them. Each insulin monomer making up the hexamer is coloured differently.

Chemical Storylines sections

• EP1 Christopher's story
• EP2 Protein building
• EP3 Genetic engineering
• EP4 Proteins in 3D
• EP5 Giving evolution a push
• EP6 Enzymes
• EP7 Summary

Chemical Ideas sections

• 3.3 Shapes of molecules (revision)
• 3.5 Geometric isomerism (revision)
• 3.6 Optical isomerism
• 5.3 Forces between molecules: temporary and permanent dipoles (revision)
• 5.4 Forces between molecules: hydrogen bonding (revision)
• 6.6 Nuclear magnetic resonance spectroscopy
• 7.1 Chemical equilibrium (revision)
• 7.2 Equilibria and concentrations
• 10.2 The effect of temperature on rate (revision)
• 10.3 The effect of concentration on rate
• 10.5 How do catalysts work? (revision)
• 13.3 Carboxylic acids and their derivatives (revision)
• 13.4 The –OH group in alcohols, phenols and acids (revision)
• 13.8 Amines and amides (revision)
• 13.9 Amino acids

Activities

• EP2.1 Investigating amines and amino acids
• EP2.2 What’s in aspartame?
• EP2.3 Using nuclear magnetic resonance (n.m.r.) spectroscopy for structure determination
• EP2.4 The shapes of a-amino acids
• EP2.5 A testing smell
• EP2.6 Taking note of proteins
• EP2.7 Modelling DNA
• EP2.8 Life reveals its twisted secret
• EP6.1 Testing for glucose
• EP6.2 Succinate dehydrogenase (Optional extension)
• EP6.3 The effect of enzyme and substrate concentration on the rate of a reaction
• EP6.4 Using the iodine clock method to find the order of a reaction
• EP6.5 Enzyme kinetics
• EP7 Check your notes on Engineering Proteins

External links

• EP unit map
• EP Check Your Notes