USMLE Step 1 Review/Pathology

5 SIGNS OF INFLAMMATION (as described by Celsus)

• Redness/Erythema (Rubor)
• Raised temperature (Calor)
• Swelling (Tumor)
• Pain (Dolor)
• Loss of Function (Functio Laesa)

HYPERSENSITIVITY REACTIONS

Goombs classification: "Anna Cycled Immediately Downhill--Gell & Goombs" or "ACID".

• Type I Anaphylaxis
• Type II Cytotoxic-mediated
• Type III Immune-complex
• Type IV Delayed hypersensitivity