Last modified on 22 June 2009, at 10:59

Structural Biochemistry/RecA Protein

RecA can be found in E. Coli and it is needed in order to repair and maintain DNA. A structural and functional homolog for Rec A can be found in every species and as a result, it is used as a method to exchange genetic information by homologous recombination through sexual reproduction. RecA has multiple functions, all of which are related to DNA repair. Its main function which has been most widely studied is that it facilitates DNA recombination in order to repair DNA double strand breaks. The RecA protein can catalyze one directional branch migration. This function makes it possible to complete recombination. Bacterial strains such as E. Coli that are lacking RecA are useful for cloning procedures. RecA.jpg