Radiation Oncology/Cancer Syndromes/Cockayne Syndrome



Cockayne Syndrome



  • Mutations in ERCC6 and ERCC8, part of the NER pathway for single strand DNA damage repair
  • Autosomal recessive syndrome
  • Growth failure, impaired development of CNS, photosensitivity, premature aging
  • No cancer predisposition
Last modified on 11 September 2009, at 09:10