Introduction to Respiratory Care/Arterial blood gases

Many methods exist to guide the interpretation of the ABG.

Step 1: Henderseon-Hasselbach equation edit

[H+] = 24(PaCO2) / [HCO3-]

If the pH and the [H+] are inconsistent, the ABG is probably not valid.

pH Approximate [H+] (mmol/L)
7.00 100
7.05 89
7.10 79
7.15 71
7.20 63
7.25 56
7.30 50
7.35 45
7.40 40
7.45 35
7.50 32
7.55 28
7.60 25
7.65 22

Is there alkalemia of acidemia present? edit

pH < 7.35  acidemia
pH > 7.45  alkalemia
  • This is usually the primary disorder
  • You will need to check the PaCO2, HCO3- and anion gap
  • An acidosis or alkalosis may be present even if the pH is in the normal range (7.35 – 7.45)

Respiratory vs. Metabolic edit

Compensation edit

Increased anion gap edit