File:Hair Cell Patterning Defects in the Cochlea.png

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English: Scanning electron micrographs demonstrating the different patterns of hair cell production along the length of the cochlea in Jag1-cko embryos.

(A–D) Low-power views of the apical and basal cochlear turns. The boxed-in area along the base in (A) and (B) is shown at higher magnification in (C) and (D). Note the absence of hair cells in the base of the Jag1-cko cochlea, except for a small patch of cells in the more apical portion (arrow). Scale bars = 500 μm.

(E and F) In the midbasal region, more hair cells are observed, but they are arranged in patches, with no clear distinction between inner and outer hair cells.

(G and H) In the apical turn, hair cells are continuous but generally arranged in only two rows. Scale bar = 100 μm.
Date
Source The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear ([1])
Author Amy E. Kiernan, Jingxia Xu, Thomas Gridley

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13 January 2006

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current04:47, 12 February 2009Thumbnail for version as of 04:47, 12 February 20092,012 × 2,475 (3.05 MB)Mike.lifeguard{{Information |Description={{en|1=Scanning electron micrographs demonstrating the different patterns of hair cell production along the length of the cochlea in Jag1-cko embryos. (A–D) Low-power views of the apical and basal cochlear turns. The boxed-in